Kybella is the first and only FDA-approved injectable drug for dissolving submental fat and reducing the appearance of moderate to severe fat under the chin. The active ingredient in Kybella is comprised of a synthetic version of deoxycholic acid, which is a substance that occurs naturally in the body and aids in the breakdown and absorption of dietary fat. Kybella was under development for more than 9 years, by the Kythera Corporation, and has been the subject of over 20 clinical studies involving over 2,600 patients. Clinical trials went on for several years to ensure that Kybella injections were a safe and effective treatment for submental fat. Kybella treatment is designed to be injected into the targeted areas of excess unwanted fat under the chin to dissolve these fat cells.